NADH (nicotinamide adenine dinucleotide)

NADH (or NAD) is found in all living cells, where it stimulates the production of energy-storing molecules. Scientists have been aware of the importance of NADH for a long time, but unfortunately, oral doses have often been ineffective because the compound is easily destroyed by stomach acids.

NADH is therefore now available in ‘enteric-coated’ tablets designed to pass through the stomach intact and to deliver the compound to the intestines. In a recent study, NADH (daily, in enteric capsules) increased vigour and mental alertness in about a third of participants, all of whom suffered from chronic fatigue syndrome (CFS). A control placebo group showed less than 10% reported benefits. The dose used was 5 mg, taken twice a day.